Tag: Glucosamine with food

Studies have shown that continuous and consistent intake of glucosamine is more critical for its effectiveness than the specific time of day it is consumed. For most people, the ideal time to take glucosamine depends on personal preference and how their body reacts, though taking it with food is often recommended to minimize potential gastrointestinal upset.

Over 27 million adults in the U.S. have osteoarthritis, and many turn to glucosamine supplements to help manage symptoms. Knowing what is the right time to take glucosamine, such as with or without food, can optimize its effectiveness and minimize potential side effects.

While glucosamine is a naturally occurring compound that is a key building block for healthy joint cartilage, its oral bioavailability in humans is surprisingly low, around 10–12%. Due to the potential for mild gastrointestinal side effects like nausea or heartburn, many experts recommend taking glucosamine on a full stomach.