Can Vitamin C Cause Hemolytic Anemia? Understanding the Risks for G6PD Deficiency
                                
                                
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                                    4 min read                                
                            
                                Case reports and medical reviews confirm that while rare, high-dose intravenous vitamin C can cause hemolytic anemia in individuals with a specific inherited enzyme deficiency. This risk is almost exclusively limited to those with Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency, for whom excessive ascorbic acid acts paradoxically as a powerful pro-oxidant.