Tag: High dose niacinamide

According to the National Institutes of Health, the tolerable upper intake level (UL) for niacinamide from supplements is 900 mg per day for adults, based on data regarding potential gastrointestinal effects. A daily oral dose of 2000 mg of niacinamide, therefore, significantly exceeds this safety threshold and is considered too much for most individuals.

According to numerous clinical trials, supplementing with nicotinamide has shown effectiveness for certain conditions like skin cancer prevention. However, while some doses are generally well-tolerated for most, understanding the specific safety profile and potential side effects of taking nicotinamide is crucial.

While the recommended daily intake of niacin for adults is around 14–16 mg, research suggests that oral niacinamide is possibly safe for most adults when used appropriately under medical guidance. Taking higher amounts should only be done under medical supervision.