Tag: Hyperlysinemia

According to UCSF Health, the normal plasma range for lysine in adults is 150 to 220 µmol/L, while for children, it's 120 to 290 µmol/L. Lysine is an essential amino acid, which means the body cannot produce it on its own and must obtain it through diet.

While lysine is an essential amino acid necessary for human health, excessive intake, particularly from supplements, can lead to adverse health effects. What happens with too much lysine can range from mild digestive upset to more serious long-term complications, though these are rare. Most people get enough lysine from their diet and do not require supplementation, and overconsumption is usually tied to high supplement use.

A 2020 review of a study on freshwater fish indicated potential hepatotoxicity and nephrotoxicity from acute high doses of L-lysine supplements. Anyone considering supplementation must understand who should avoid L-lysine, especially if they have pre-existing health conditions or are taking certain medications.

While L-lysine is generally considered safe for most people at recommended doses for a limited time, some individuals with pre-existing conditions, or those who are pregnant or breastfeeding, should either avoid or use extreme caution before taking it.

According to the National Institutes of Health, proper lysine catabolism is crucial, as its malfunction can lead to severe neurometabolic disorders like hyperlysinemia. This guide explains how to break down lysine through the body's complex biochemical pathways.

Genetic mutations can impair the body’s ability to properly metabolize lysine, leading to a cluster of inherited metabolic disorders. Understanding **what are the diseases associated with lysine** is crucial, as they can range from benign conditions to severe neurological disorders affecting growth and development.