Tag: Hypophosphatemic rickets

According to the National Institutes of Health, hypophosphatemia, or low phosphate levels in the blood, is a hallmark of all forms of rickets. The crucial role of phosphate in rickets stems from its essential function in bone mineralization and growth plate development, with deficiency leading to soft, weakened bones and deformities.

According to the National Institutes of Health, while vitamin D deficiency is the most frequent cause globally, rickets can also be triggered by a complex array of genetic and metabolic conditions. Understanding which disease causes rickets is critical for proper diagnosis and effective treatment, as the underlying cause dictates the appropriate course of action.