Tag: Hyposensitivity

Genetics play a significant role in how our bodies process stimulants, leading to vast individual differences in caffeine response. This means for some, the question, 'can you be non-responsive to caffeine?' is a very real, scientifically-backed phenomenon, resulting in little to no stimulant effect from a normal dose.

According to research, around 10% of people carry a genetic variant that makes them hyposensitive to caffeine, a primary reason why you have never felt the effects of caffeine. This lack of impact is less about a failure of the stimulant itself and more about the intricate interplay of individual biology and daily habits.