Tag: Intramuscular b12

According to a 2018 Cochrane Review, high-dose oral vitamin B12 can be as effective as intramuscular injections for correcting serum levels in many people with deficiencies. The question remains, however: should you inject B12 into muscle for specific health needs, and if so, when is it necessary?

While intramuscular (IM) B12 injections have long been the gold standard for treating severe deficiencies, a 2019 study published in *Drug Delivery and Translational Research* found that sublingual B12 significantly increased serum B12 levels, sometimes even more effectively than IM injections. This challenges the traditional view and prompts a closer look at whether sublingual B12 is truly a better option for some individuals.