Will Vinegar Stop Jalapeno Burn? The Acidic Truth
                                
                                
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                                    3 min read                                
                            
                                Capsaicin, the chemical compound that makes jalapenos and other chili peppers hot, is a hydrophobic molecule, meaning it doesn't mix with water. This is why reaching for a glass of water when your mouth is on fire is often an exercise in futility, making alternative solutions necessary.