Tag: Large pepperoni pizza

According to Domino's, a single slice of a large hand-tossed pepperoni pizza contains 280 calories. However, this number is not universal, as the calorie count can vary significantly based on the crust, cheese, and toppings selected. A large pizza is typically cut into eight slices, but the specific combination of ingredients is the most important factor in determining the nutritional information.

According to nutritional experts, a single slice of a large pepperoni pizza from Domino's can contain over 13 grams of protein. However, the total amount of protein in a large Domino's pizza varies dramatically based on the specific toppings and crust chosen, with meat-heavy options offering a significant protein boost.