How is lathyrism caused? Understanding the neurotoxic legume and risk factors
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3 min read
Hippocrates first described a neurological disorder caused by *Lathyrus* seed consumption in 400 BC, making lathyrism one of the oldest known neurotoxic diseases. It is primarily caused by the overconsumption of legumes from the *Lathyrus* genus, particularly the grass pea (*Lathyrus sativus*), which contain harmful neurotoxins. This debilitating, irreversible condition is a major public health issue in regions facing drought and famine, where the resilient grass pea becomes a primary food source.
