Tag: Liver iron concentration

The human body lacks a natural mechanism to excrete excess iron, leading to its accumulation in organs like the liver and heart. This systemic iron overload can cause significant organ dysfunction and premature mortality if left untreated. For this reason, understanding the threshold for iron chelation is critical for timely therapeutic intervention and effective patient management.

Iron overload is a leading cause of organ damage and mortality in individuals with thalassemia, with levels significantly increasing after just one year of chronic transfusions. Understanding **how much iron is too much for thalassemia** is critical for preventing life-threatening complications, especially affecting the heart and liver.