How many calories does a homemade meatball sub have?
                                
                                
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                                    4 min read                                
                            
                                According to several recipe developers, a typical homemade meatball sub can contain anywhere from 400 to over 780 calories, depending heavily on the specific ingredients and portion sizes used. The answer to "How many calories does a homemade meatball sub have?" isn't a single number, but a range determined by your choice of bread, meat, cheese, and sauce.