Hi-C vs. Micro-C: What is the Difference Between Hi C and MicroC Assays?
                                
                                
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                                    3 min read                                
                            
                                According to scientific studies, Micro-C is an improved variant of Hi-C, capable of capturing genome-wide DNA interactions with significantly higher resolution. The fundamental difference between Hi C and Micro C lies in their distinct methods for fragmenting chromatin during the procedure for mapping the three-dimensional (3D) structure of the genome.