Tag: Mocd

Molybdenum deficiency is extremely rare in healthy people, with adequate intake typically coming from a balanced diet. The severe disease most often associated with the inability to utilize this trace mineral is a rare genetic condition known as Molybdenum Cofactor Deficiency (MoCD).

Molybdenum deficiency in healthy humans is extremely rare, with documented cases almost exclusively tied to a rare genetic disorder known as Molybdenum Cofactor Deficiency (MoCD). This inherited metabolic disease prevents the body from utilizing the trace mineral, leading to severe and often fatal consequences shortly after birth.

Molybdenum cofactor deficiency (MoCD) is a rare, inherited metabolic disorder, estimated to occur in 1 in 100,000 to 200,000 newborns, and is the primary condition associated with molybdenum deficiency. This metabolic defect leads to a buildup of toxic substances, causing profound and progressive brain dysfunction, seizures, and developmental delay.

Although incredibly rare, a deficiency in the essential trace mineral molybdenum can have severe consequences for the body. A lack of molybdenum disrupts critical enzyme functions, primarily impacting metabolic pathways involving sulfur amino acids and purines.

True dietary molybdenum deficiency is extremely rare, with only one documented case in a patient on long-term total parenteral nutrition (TPN) lacking molybdenum. For most people, concern over *what are the symptoms of low molybdenum* is more accurately related to the severe and often fatal genetic disorder, Molybdenum Cofactor Deficiency (MoCD).