Why Does Centrum Upset My Stomach? Common Reasons and Solutions
                                
                                
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                                    4 min read                                
                            
                                According to research, highly concentrated nutrients and minerals are a primary reason many multivitamins, including Centrum, cause gastrointestinal distress. Taking supplements on an empty stomach can lead to feelings of nausea, cramping, or general discomfort, particularly due to high levels of specific ingredients.