Tag: Neuroendocrinology

The hypothalamus is a small, almond-sized structure deep within the brain that serves as the body’s central control center for many essential functions, including energy balance. In fact, this vital area is a master regulator, integrating hormonal signals to influence appetite, energy expenditure, and overall metabolic health.

In rodents, food deprivation for as little as 24 hours has been shown to significantly increase the expression and release of neuropeptide Y (NPY). This powerful surge of NPY during periods of energy deficit is part of a sophisticated physiological response aimed at promoting food intake and restoring energy balance.