Tag: Neuroenergetics

The brain, despite making up only 2% of total body weight, accounts for approximately 20% of the body's total glucose consumption while at rest. This fact confirms that yes, the brain can use glucose for energy, and it is in fact its primary and preferred fuel source.

Despite its small size, consuming a massive 20-25% of the body's total energy, the brain has long been associated with glucose as its primary fuel source. The question, 'What is the only energy source the brain can use?' is a common one, but the answer reveals a surprising metabolic flexibility that allows the brain to utilize alternative fuels during specific conditions.

Despite making up only about 2% of total body weight, the human brain demands 20-25% of the body's resting energy consumption. The concept of brain calories refers to this remarkably high metabolic rate needed to fuel its continuous operations, whether you are awake, asleep, or simply relaxing.