Tag: Niacinamide toxicity

According to the National Institutes of Health, the tolerable upper intake level (UL) for niacinamide from supplements is 900 mg per day for adults, based on data regarding potential gastrointestinal effects. A daily oral dose of 2000 mg of niacinamide, therefore, significantly exceeds this safety threshold and is considered too much for most individuals.

Studies have shown that while nicotinamide is generally well-tolerated at typical doses, high oral intakes, such as over 3,000 mg daily, can lead to more serious adverse effects. Understanding what are the symptoms of too much nicotinamide is crucial for anyone considering high-dose supplementation.