Tag: Nicotinamide riboside risks

While NAD+ precursors are widely studied for their potential benefits in cellular health and longevity, a growing number of anecdotal and clinical reports have raised concerns about over-supplementation. While the body naturally regulates its NAD+ levels, an excessive intake of supplements may overwhelm the system, leading to uncomfortable and potentially serious health issues.

Cellular NAD+ levels decline by an estimated 10-80% as we age, fueling a booming market for supplements and therapies promising to restore youthful vitality. However, what are the negatives of NAD+ that these marketing campaigns often overlook? While generally safe in the short term, potential risks and adverse effects warrant a closer look before starting supplementation.