Tag: Nitrous oxide abuse

Chronic nitrous oxide abuse is a rising public health concern that can cause severe and sometimes irreversible neurological damage by creating a functional B12 deficiency. This article delves into the irreversible chemical process of how long does nitrous oxide inactivate B12, the subsequent health risks, and the necessary steps for nutritional recovery.

According to a 2023 systematic review, elevated homocysteine and methylmalonic acid levels were found in about 80% of symptomatic recreational nitrous oxide users, indicating a functional vitamin B12 deficiency. This insidious effect can lead to severe neurological complications, even if serum B12 levels appear normal.