Tag: Nutrient sensing

Based on research from the University of Southern California, a cyclical fasting-mimicking diet (FMD diet) can lower risk factors for chronic diseases and promote cellular rejuvenation. This unique dietary approach is designed to mimic the metabolic effects of fasting while still allowing for some food intake, making it more manageable for many individuals.

According to a 2016 World Health Organization report, the global prevalence of overweight and obesity has more than doubled since 1980, a phenomenon heavily influenced by our food choices. Understanding how likes and dislikes of foods are linked to homeostasis reveals the intricate biological and psychological systems that regulate energy balance and can be overridden by modern dietary habits.

Recent scientific studies have revealed that humans may possess a unique oral sensation for complex carbohydrates, a finding that challenges the long-held belief that only simple sugars register as 'sweet'. This discovery suggests that the human palate can indeed perceive the 'starchy' flavor of foods like bread and rice, even when sweet receptors are blocked. Understanding this mechanism offers new insights into our cravings for carb-rich foods and the complexities of human taste perception.

According to the World Health Organization, the global population of people aged 65 or older is projected to double by 2050, underscoring the growing need to understand factors influencing healthy longevity. What we eat plays a fundamental role in this process, significantly impacting aging on a cellular level and influencing our risk of age-related diseases.

According to research published in *PLoS ONE*, a 72-hour fast significantly reduces mTOR activation in human skeletal muscle. The question, "Does fasting increase or decrease mTOR?" is central to understanding the cellular mechanisms behind fasting's benefits, including longevity and enhanced cellular repair. This article explores how fasting acts as a potent negative regulator of the mTOR signaling pathway.

According to extensive research at the University of Southern California's Longevity Institute, Fasting Mimicking Diets (FMDs) like ProLon NR 3 are designed to provide the benefits of prolonged fasting while still allowing for a limited intake of food. Developed by Dr. Valter Longo, this dietary approach is formulated to trick the body into a fasting state, activating key cellular processes that promote overall health and rejuvenation.

According to extensive research, the process of autophagy is most potently activated during periods of nutrient deprivation, and is rapidly inhibited by the presence of nutrients, including amino acids. This raises the critical question: do aminos stop autophagy, and if so, how does this occur? This article dives into the cellular mechanisms behind this phenomenon.

Autophagy, the body's natural cellular cleansing process, is typically induced during periods of nutrient deprivation, such as fasting. This has led many to question: **Does broth stop autophagy?** While bone and other broths are often praised for their nutrient density, their caloric and amino acid content can interfere with the signaling pathways that regulate this critical cellular process, making the answer more nuanced than a simple 'yes' or 'no'.