Can one meal spike your cholesterol? The surprising truth about acute and chronic dietary effects
                                
                                
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                                    4 min read                                
                            
                                While a single high-fat meal can cause a temporary rise in triglycerides, the idea that one meal can spike your cholesterol is largely a myth. Your body's robust homeostatic mechanisms prevent such drastic, immediate changes, with lasting effects depending on your long-term dietary patterns.