Tag: Parenteral nutrition associated liver disease

Although Total Parenteral Nutrition (TPN) can be a life-saving therapy for individuals unable to use their digestive tract, studies show a high incidence of complications, particularly with long-term use. A significant medical concern that patients and healthcare providers must address is **what condition is associated with long-term TPN**, specifically Parenteral Nutrition-Associated Liver Disease (PNALD). This progressive liver dysfunction can lead to severe health issues, making a deep understanding of its causes and management critical for patient safety and well-being.

According to the Cleveland Clinic, long-term parenteral nutrition-associated liver disease (PNALD) can affect up to 50% of patients after five to seven years. This statistic underscores why is TPN not good long-term and why healthcare providers prioritize transitioning to alternative nutritional methods whenever possible.

Affecting up to 50% of adults on prolonged treatment, parenteral nutrition-associated liver disease (PNALD) is a significant risk associated with total parenteral nutrition (TPN). While a life-sustaining therapy for those with non-functional gastrointestinal tracts, it can lead to various serious complications that necessitate careful monitoring and management.