Tag: Pegvaliase

Affecting approximately 1 in 25,000 newborns in the United States, phenylketonuria (PKU) is a rare genetic metabolic disorder that, if untreated, can cause severe intellectual disability. The cornerstone of what exactly is PKU treatment has always been a strict, low-phenylalanine diet, but advancements in medical therapy now offer additional management options.

Most US facilities recommend maintaining phenylalanine levels in the range of 2 mg/dL to 6 mg/dL for individuals with phenylketonuria. Effectively managing a PKU diet is a lifelong commitment that involves strict dietary restrictions to control blood phenylalanine levels and prevent neurological damage.