Tag: Plasma donation side effects

According to the NIH Clinical Center, your body can replace lost plasma fluids within 48 hours. However, some donors wonder, "Does donating plasma deplete you of nutrients?" The process can temporarily lower levels of specific components, but your body is highly efficient at self-replenishment with proper care.

While it's not a weight-loss solution, research indicates your body can burn hundreds of calories by donating plasma, with some sources citing estimates of 450 to 650 calories per session. This energy expenditure is a result of the metabolic work required for the body to replenish the lost plasma proteins and fluids, a process that continues for up to 72 hours after your visit.