Tag: Polyphenol drug interactions

According to extensive experimental studies, certain polyphenols, particularly in high doses, may have genotoxic effects or interfere with thyroid hormone biosynthesis. The potential problems with polyphenols are primarily linked to the consumption of high-dose supplements rather than intake from a balanced diet, raising important safety considerations.

An estimated 25% of the global population is affected by iron deficiency, a condition that can be worsened by high polyphenol intake. While generally safe in dietary amounts, certain individuals and medical conditions restrict or advise caution when consuming polyphenols, particularly in concentrated supplement form.