Tag: Primates

Approximately 40 million years ago, a pivotal genetic mutation occurred in our primate ancestors, inactivating a key gene and setting the stage for one of the most significant metabolic differences between humans and most other mammals: our inability to produce vitamin C. This means that for our body to have this vital nutrient, we must consume it through food or supplements.

While most animals can produce their own vitamin C, a significant number of species have lost this ability through evolution and must obtain it from their diet. This guide explains exactly what species require vitamin C and the genetic reason behind this dependency.

According to genetic studies, the inability of certain animals to produce their own vitamin C is due to a mutation in the GULO gene. This gene encodes the final enzyme in the ascorbic acid biosynthesis pathway, rendering affected species dependent on dietary intake.