Tag: Proline side effects

While proline is a vital amino acid that helps produce collagen and supports tissue repair, excessively high levels in the body can lead to a range of adverse health effects. Typically, a healthy body regulates proline levels effectively, but inherited metabolic disorders or high-dose supplementation can disrupt this balance.

Studies suggest a potential link between high dietary proline and increased depression risk, particularly when gut microbiota are altered. It is also possible to have too much proline due to underlying metabolic issues, emphasizing that excess is primarily caused by genetic factors or over-supplementation, not a normal diet.

According to the National Institutes of Health, L-proline is a crucial component of collagen, a protein that constitutes about one-third of the body's total protein. As a fundamental building block of connective tissues, the question of whether proline is good or bad is relevant for anyone concerned with structural health, from skin elasticity to joint integrity.