Tag: Pseudohypocalcemia

Approximately 40% of the total calcium in your blood is bound to plasma proteins, primarily albumin. Therefore, a drop in albumin levels, a condition known as hypoalbuminemia, directly impacts the measurement of total serum calcium, creating a lab result that suggests hypocalcemia.

Approximately 40% of the body's calcium circulates bound to a protein called albumin. This is the key reason why a low albumin can cause low calcium levels to be reported in a standard blood test, a phenomenon known as pseudohypocalcemia, without a true deficiency of active calcium.