How Do You Treat Hereditary Folate Malabsorption?
•
4 min read
Hereditary folate malabsorption (HFM) is a rare autosomal recessive disorder caused by a defective gene (SLC46A1) that impairs folate transport into the body and brain. Early diagnosis and targeted treatment with reduced folates, such as folinic acid, are critical for correcting both systemic and neurological folate deficiencies. Proper management is essential for preventing severe symptoms, especially in infants who cannot absorb folate from milk or formula after birth.
