Tag: Rls causes

According to a 2022 study published in *Clinical Neurology and Neurosurgery*, a significant correlation exists between low serum vitamin B12 levels and the severity of Restless Legs Syndrome (RLS) symptoms. This raises a critical question: can low B12 cause RLS directly, or is it a contributing factor? The link is more complex than a simple yes or no.

According to the Restless Legs Syndrome Foundation, iron deficiency is a well-known contributor to RLS, but a less-discussed association exists: can folic acid deficiency cause restless legs? Studies show a link, particularly in certain patient groups, with folic acid playing a crucial role in nervous system function and neurotransmitter production.