Why does fat have the lowest RQ?
                                
                                
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                                    4 min read                                
                            
                                The respiratory quotient (RQ) is a critical measure in biochemistry, with the average human RQ on a mixed diet being around 0.8. This simple ratio of carbon dioxide produced to oxygen consumed reveals which macronutrient—fats, carbohydrates, or proteins—is primarily being metabolized. Uniquely, fat has the lowest RQ among all macronutrients, a phenomenon rooted in its chemical composition and metabolic pathway.