Tag: Sapropterin

Affecting approximately 1 in 25,000 newborns in the United States, phenylketonuria (PKU) is a rare genetic metabolic disorder that, if untreated, can cause severe intellectual disability. The cornerstone of what exactly is PKU treatment has always been a strict, low-phenylalanine diet, but advancements in medical therapy now offer additional management options.

Phenylketonuria (PKU) is a rare genetic disorder affecting approximately 1 in 13,500 to 19,000 newborns in the United States. It is a condition where the body cannot properly metabolize the amino acid phenylalanine (Phe), leading to toxic buildup and developmental issues.

Phenylketonuria (PKU), a rare genetic disorder, affects approximately 1 in 25,000 newborns in the U.S. and requires careful lifelong management of phenylalanine levels. For those with PKU, learning how to reduce phenylalanine is essential to prevent severe health complications, particularly to the brain.

Most US facilities recommend maintaining phenylalanine levels in the range of 2 mg/dL to 6 mg/dL for individuals with phenylketonuria. Effectively managing a PKU diet is a lifelong commitment that involves strict dietary restrictions to control blood phenylalanine levels and prevent neurological damage.