How is diosmin made? Exploring the industrial synthesis process
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4 min read
Diosmin, a flavonoid commonly used to treat venous diseases, is predominantly manufactured through a semi-synthetic process starting from another flavonoid found in citrus peels. This manufacturing route is necessary because the concentration of diosmin in citrus fruits is too low for cost-effective extraction, whereas the starting material, hesperidin, is abundant. The process transforms the hesperidin molecule into the desired diosmin via a series of chemical reactions.
