Why Does Thiamine Deficiency Cause Megaloblastic Anemia?
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5 min read
While commonly associated with deficiencies in B12 or folate, a rare genetic disorder known as Thiamine-Responsive Megaloblastic Anemia (TRMA) syndrome demonstrates a direct link, showing why does thiamine deficiency cause megaloblastic anemia. This condition arises from a malfunction in the body's ability to transport thiamine into cells, impairing critical metabolic pathways essential for DNA synthesis.
