Tag: Spermidine side effects

While spermidine is a naturally occurring polyamine that is vital for cell health, its levels decline as we age. While supplemental spermidine is generally safe at recommended doses, research shows there is a potential for adverse effects with excessive intake, especially from poorly regulated sources.

Spermidine is a naturally occurring polyamine found in our cells and a variety of foods, but for those considering supplementation, a common question arises: does spermidine have side effects? Clinical studies suggest that for most healthy adults, adverse effects are typically mild, manageable, and often dose-dependent, with overall safety appearing favorable at recommended intake levels.

While generally considered safe, some people have reported mild side effects, including headaches, from spermidine supplements. This polyamine is naturally present in the body and many foods, but adverse effects can sometimes occur with supplementation, especially when starting a new regimen or taking higher doses. It is important to understand the factors that may contribute to this issue and how to manage it safely.