Is Sumac Unhealthy? Separating Fact from Poisonous Fiction
                                
                                
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                                    2 min read                                
                            
                                According to a 2025 systematic review of clinical trials published in the National Institutes of Health database, sumac supplementation significantly reduced hs-CRP concentrations in adults, suggesting potential anti-inflammatory benefits. The good news is that culinary sumac is generally safe and healthy, but a dangerous lookalike has fueled misconceptions about its safety for years.