How Long Does It Take for Aspartame to Get Out of Your System? A Look at Metabolism
                                
                                
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                                    6 min read                                
                            
                                After ingestion, aspartame is rapidly and completely broken down by digestive enzymes in the small intestine, meaning that in its original form, it is never found circulating in the bloodstream. So, the answer to "how long does it take for aspartame to get out of your system?" depends on how long it takes to process its components.