Tag: Topical cream

The U.S. Food and Drug Administration (FDA) has designated D-panthenol as "Generally Recognized As Safe and Effective" (GRAS) for use as a dietary supplement and food ingredient. This official classification confirms its safety for ingestion when manufactured for that specific purpose, though it’s essential to distinguish between edible and topical forms.

Vitamin B12 is a complex, water-soluble molecule, and for this reason, it is generally not effectively absorbed passively through the skin. However, while traditional topical creams offer poor systemic absorption, emerging technologies like microneedle patches are being developed to help answer the question, "Can vitamin B12 be absorbed through the skin?".