Should TPN be discarded? A comprehensive guide to safety and handling
                                
                                
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                                    5 min read                                
                            
                                According to the United States Pharmacopeia (USP) guidelines, Total Parenteral Nutrition (TPN) solutions have a maximum hang time of 24 hours to prevent microbial contamination. Therefore, yes, unused portions of a TPN bag must be discarded to maintain patient safety.