How long can TPN hang before needing to be changed?
                                
                                
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                                    5 min read                                
                            
                                According to the U.S. Pharmacopeia (USP) guidelines for sterile compounding, a total nutrient admixture (TNA) should not exceed a 24-hour infusion period. Understanding how long can TPN hang before needing to be changed is critical for preventing microbial contamination, which can lead to serious infections. This guideline applies to most standard parenteral nutrition solutions, but different factors can affect the maximum allowable hang time.