Tag: Trisomy 21

Studies have shown that abnormal maternal folate metabolism can promote chromosomal instability, which is a potential mechanism linked to trisomy 21. However, the role of folate in preventing Down syndrome is complex and distinct from its confirmed effectiveness in preventing other birth defects.

Studies show that people with Down syndrome have a resting metabolic rate that is 10 to 15 percent lower than their typically-developing peers. This critical metabolic difference means that people with Down syndrome need less calories to maintain a healthy weight, making dietary management a key component of their overall health.