Can Lack of Intrinsic Factors Cause Anemia?
                                
                                
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                                    4 min read                                
                            
                                According to the National Institutes of Health, pernicious anemia is the most common cause of clinically evident vitamin B12 deficiency worldwide. The answer is a definitive yes: a lack of intrinsic factors can cause anemia, specifically pernicious anemia, by preventing the body from absorbing vitamin B12.