Does a Vitamin B Injection Hurt? What to Expect
                                
                                
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                                    4 min read                                
                            
                                According to the NHS, pain, swelling, or itchy skin at the injection site is a common and usually mild side effect of hydroxocobalamin injections, a common form of vitamin B12. In general, the question, "Does a vitamin B injection hurt?" can be answered with a reassuring "not usually," as most people report only a brief stinging or minor soreness, comparable to other common vaccines.