Tag: Vldl

A significant portion of the fat circulating in your body, about 70%, is synthesized internally rather than consumed from food. These are known as endogenous fats, and their production is a complex metabolic process essential for energy storage and distribution.

According to the Centers for Disease Control and Prevention (CDC), nearly 86 million adults in the United States had high cholesterol in 2020. High levels of 'bad' cholesterol, specifically VLDL and LDL, significantly increase the risk of heart disease and stroke.

Severe protein-calorie malnutrition, particularly the form known as kwashiorkor, has long been associated with the characteristic symptom of fatty liver, or hepatic steatosis. While once thought to be a simple lack of protein, research has revealed complex metabolic mechanisms explaining why and how protein malnutrition cause steatosis.

Recent studies on animal models suggest that naringenin can significantly reduce plasma cholesterol and triglycerides. This article explores the intricate mechanisms by which naringenin affects cholesterol levels and offers potential benefits for cardiovascular health, including how it might positively influence lipid metabolism.

Approximately 95% of dietary lipids are absorbed in the small intestine, but because they are water-insoluble, they require a specialized transport system. The primary transport vehicles for these digested fats are spherical lipoprotein particles known as chylomicrons. This system is critical for distributing energy and essential nutrients derived from dietary fats throughout the body.

According to the Cleveland Clinic, VLDL cholesterol levels above 30 mg/dL are considered high, a finding that is often estimated using the calculation of triglyceride/5. This method helps determine which lipoprotein can be estimated by measuring the triglyceride level and dividing by 5, providing insight into your cardiovascular health.

Approximately 30% of the U.S. population has elevated plasma triglyceride levels. The lipoprotein responsible for carrying the most triglycerides is the chylomicron, a large particle that transports dietary fats from the intestines to body tissues. Understanding this process is key to comprehending overall lipid metabolism and its implications for health.

Due to their insolubility in water, lipids such as triglycerides and cholesterol require special carriers to navigate the body's watery bloodstream. This crucial task is performed by various types of lipoproteins, which facilitate the transport of these fats to and from different tissues for energy, storage, or processing.

While obesity is typically associated with fatty liver disease, the opposite, undernutrition, can also cause it. The development of a fatty liver is a consistent and defining feature of the protein-energy malnutrition disorder known as kwashiorkor, making its mechanism a paradox worthy of examination.

Did you know that a choline deficiency can cause fatty liver disease and liver damage in humans? This essential nutrient plays a fundamental role in lipid metabolism, ensuring the proper transport and processing of fats throughout the body.