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Understanding the Best Time to Take Magnesium Glycinate and Citrate

4 min read

While approximately half of the U.S. population fails to meet the recommended daily intake of magnesium, proper timing can significantly influence the effectiveness of supplements. Understanding what is the best time to take magnesium glycinate and citrate is key to achieving your specific health goals, whether for better sleep or improved digestion.

Quick Summary

This guide details the optimal timing for magnesium glycinate versus magnesium citrate, explaining how their different forms and functions affect when they should be taken for maximum benefit. Learn to tailor your intake for relaxation, sleep support, or digestive relief, prioritizing consistency and avoiding potential side effects.

Key Points

  • Evening for Glycinate: For promoting sleep and relaxation, take magnesium glycinate about 30-60 minutes before bed.

  • Flexible for Citrate: Time your magnesium citrate based on your need for constipation relief, remembering effects can start within 30 minutes to 6 hours.

  • Consistency Over Timing: For general health and managing a deficiency, maintaining a consistent daily schedule is more important than the exact time.

  • With Food is Best: Take magnesium with a meal to enhance absorption and minimize the risk of digestive side effects.

  • Check for Interactions: Always take magnesium supplements 2-4 hours apart from other medications like certain antibiotics and osteoporosis drugs.

In This Article

Different Magnesium Forms for Different Needs

Magnesium is a vital mineral involved in over 300 biochemical reactions within the body, influencing everything from muscle and nerve function to blood pressure regulation. The specific benefits and absorption characteristics of magnesium supplements can vary widely depending on the compound it is bound to. For example, magnesium glycinate and magnesium citrate offer distinct advantages that make their optimal timing different.

Magnesium glycinate is a chelated form, meaning it's bound to glycine, an amino acid with its own calming properties. This highly bioavailable form is generally gentle on the stomach and is primarily sought for its anxiolytic and sleep-supporting effects. In contrast, magnesium citrate combines magnesium with citric acid. While it is also well-absorbed, it acts as an osmotic laxative, drawing water into the intestines to encourage bowel movements.

Timing for Magnesium Glycinate: For Sleep and Relaxation

For those seeking relaxation, stress reduction, or sleep improvement, the evening is the optimal time to take magnesium glycinate. The calming effects of both magnesium and the amino acid glycine are most effective when taken before bed.

How to Time Your Glycinate Dose for Sleep

  • Evening Dosage: Take your magnesium glycinate supplement approximately 30 to 60 minutes before you plan to go to sleep. This allows time for the supplement to be absorbed and its calming effects to begin working on the nervous system.
  • Why the Evening? Magnesium helps regulate the neurotransmitter GABA, which promotes calmness, while glycine can also support deeper sleep. This combined effect helps reduce the time it takes to fall asleep and can improve overall sleep quality.
  • For Daytime Stress: If your primary goal is to manage daily stress or muscle tension, some people may benefit from splitting their dose, taking a smaller amount in the morning and the rest in the evening. This provides a calming effect throughout the day without causing significant daytime drowsiness.

Timing for Magnesium Citrate: For Digestion and General Use

Magnesium citrate's timing is driven by its function. For its laxative effect, the timing depends entirely on when you want relief. For general, long-term health, consistency is more important than the specific time of day.

How to Time Your Citrate Dose

  • For Constipation Relief: Magnesium citrate works as a saline laxative, with effects typically occurring anywhere from 30 minutes to 6 hours after consumption. For a morning bowel movement, taking it in the evening might be appropriate. If you need more immediate relief, a morning dose is an option, but be sure you have access to a bathroom.
  • For General Health: For most people taking magnesium citrate for general well-being, the specific timing is less critical than consistency. Taking it at a regular time each day—such as with a morning or evening meal—is recommended to maintain stable magnesium levels.
  • Meal Timing: Taking magnesium citrate with food can help mitigate potential digestive side effects like stomach upset or diarrhea. For its use as a laxative, however, some products may recommend taking it on an empty stomach with a full glass of water, so always follow the product label.

Comparison: Magnesium Glycinate vs. Citrate Timing

Feature Magnesium Glycinate Magnesium Citrate
Primary Purpose Relaxation, anxiety reduction, sleep support Occasional constipation, general health
Optimal Timing Evening, 30-60 minutes before bed Flexible: Varies based on desired effect; often evening for morning relief or consistent daily intake
Primary Effect Calming the nervous system, muscle relaxation Osmotic laxative effect, softens stools
Digestive Impact Gentle on the stomach, lower risk of digestive upset Higher potential for laxative effects, especially at higher doses
Bioavailability High, well-absorbed High, well-absorbed

Other Important Considerations for Supplementing

Beyond the specific timing for each form, there are overarching best practices that apply to all magnesium supplementation:

  • Consistency is Crucial: For long-term benefits like maintaining consistent magnesium levels or managing a deficiency, daily and consistent use is more important than the exact time of day. Establish a routine you can stick to.
  • Take with Food: Regardless of the type, taking magnesium with food can help minimize the risk of digestive issues like diarrhea or nausea. This is particularly important for individuals with sensitive stomachs.
  • Split the Dose: If taking a higher dose, splitting it into two smaller amounts throughout the day can improve absorption and reduce the chance of side effects.
  • Avoid Interactions: Magnesium can interfere with the absorption of certain medications, including some antibiotics and osteoporosis drugs. Always take magnesium supplements at least 2-4 hours apart from these medications and consult a healthcare professional, especially if you have existing health conditions like kidney disease.
  • Listen to Your Body: Individual responses to supplements can vary. If you experience drowsiness during the day with magnesium glycinate, move your dose to the evening. If magnesium citrate affects you too quickly at night, switch to a morning dose.

Conclusion

Choosing the optimal time to take magnesium glycinate or citrate depends on your specific wellness goals. For those seeking to promote relaxation and restful sleep, magnesium glycinate is best taken in the evening, leveraging its calming properties. Conversely, if you need digestive support, magnesium citrate's timing is dictated by when you desire its laxative effect. While consistency is paramount for both, integrating your chosen supplement into a routine that aligns with its primary purpose is the most effective approach. Always consult a healthcare provider before beginning any new supplement regimen to ensure it's appropriate for your health status and needs.

Frequently Asked Questions

It is generally not recommended to take them at the same time, especially if taking higher doses. Magnesium citrate can have a strong laxative effect, while glycinate is milder. It may be better to use them for different purposes at separate times, or if combining, to be mindful of the total dosage and potential for digestive issues.

Taking magnesium supplements with food is generally recommended to improve absorption and reduce the likelihood of digestive side effects, such as diarrhea, nausea, or cramping.

While individual responses vary, some people notice improved sleep quality and reduced sleep latency within a week, while others may take longer. Consistency is key for long-term benefits.

Unlike magnesium glycinate, magnesium citrate does not typically promote sleepiness. Its primary effect is as a laxative, so any perceived relaxation is more related to its digestive action rather than a direct calming effect on the nervous system.

Yes, splitting doses can be an effective strategy, especially if you are using different forms for different benefits, such as magnesium citrate in the morning for digestion and magnesium glycinate in the evening for sleep.

If you miss a dose, take it as soon as you remember. However, if it's close to your next scheduled dose, it's best to skip the missed one and continue with your normal schedule. Do not take a double dose.

Common side effects include nausea, diarrhea, and stomach cramps, especially with higher doses. Magnesium glycinate is less likely to cause digestive issues than magnesium citrate. Overdosing can lead to more serious symptoms like confusion and low blood pressure.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.