What are polysaccharide tablets used for?

December 23, 2025 •

3 min read

Clinical research indicates that iron polysaccharide complex, often in tablet form, is a highly effective and well-tolerated oral iron supplement used to address dietary deficiencies. So, what are polysaccharide tablets used for? The core function of these supplements is to prevent and treat iron deficiencies and the resulting anemia.

Quick Summary

Polysaccharide tablets, which contain a chelated form of iron, are used to treat and prevent iron deficiency and anemia by improving low iron levels and replenishing body stores.

Key Points

Anemia Treatment: Polysaccharide tablets are primarily used to treat and prevent iron deficiency anemia by boosting hemoglobin production.
Improved Tolerability: Encased in a polysaccharide matrix, the iron is released slowly, causing fewer gastrointestinal side effects than traditional iron salts.
Higher Bioavailability: The complex structure ensures a more efficient absorption of elemental iron into the body.
Beneficial for Pregnancy: It is a common supplement for pregnant women with increased iron needs, helping to prevent maternal anemia.
Long-term Supplementation: The high tolerance makes it suitable for individuals with chronic blood loss or conditions like chronic kidney disease that require ongoing iron therapy.
Dietary Considerations: Absorption can be affected by food and other medications, so it's important to follow specific intake instructions.

What is a Polysaccharide Tablet?

Polysaccharide tablets most commonly refer to supplements containing polysaccharide iron complex (PIC). This oral iron formulation encases elemental iron within a polysaccharide matrix. This structure is designed for improved iron absorption and fewer gastrointestinal side effects compared to older iron salts like ferrous sulfate. The matrix allows for a slower, more controlled release of iron in the digestive tract, which is less irritating to the stomach.

Primary Medical Uses for Polysaccharide Tablets

Treating Iron Deficiency Anemia

The main use for polysaccharide tablets is treating iron deficiency anemia, a condition where insufficient iron hinders the production of hemoglobin. Anemia symptoms include fatigue and shortness of breath. The tablets provide easily absorbed iron, helping the body produce hemoglobin and replenish iron stores to reverse these symptoms.

Prevention During Pregnancy

Pregnant women need more iron to support their increased blood volume and the developing fetus. Iron deficiency anemia during pregnancy can cause complications. Polysaccharide tablets are often prescribed to prevent this and support fetal development. Their lower likelihood of causing gastrointestinal issues is particularly helpful for pregnant individuals.

Supplementation for Chronic Blood Loss

Individuals with chronic blood loss from conditions like heavy periods or gastrointestinal issues are at high risk of iron deficiency. Polysaccharide tablets are a suitable long-term supplement for these patients, helping maintain iron levels despite ongoing depletion. Managing the underlying cause of blood loss with a healthcare provider is essential, alongside supplementation.

Post-Surgery Recovery and Increased Needs

Periods of rapid growth in children and recovery from surgery also increase iron needs. Polysaccharide tablets can be used in these situations to provide the iron necessary for healing and growth. Dosing for children is adjusted based on age and weight under pediatrician supervision.

How Do Polysaccharide Iron Tablets Work?

Polysaccharide iron complex tablets work through their controlled release and high elemental iron content. The iron is bound to a large polysaccharide molecule, preventing rapid release in the stomach. This complex delivers elemental iron in a form that is readily absorbed, raising serum iron levels and boosting hemoglobin production. This slow, gradual absorption and reduced irritation make it a preferred option for those sensitive to other iron supplements.

Polysaccharide Iron vs. Other Iron Supplements

A key benefit of polysaccharide iron is its improved tolerability. The table below compares polysaccharide iron complex and ferrous sulfate:


Feature	Polysaccharide Iron Complex	Ferrous Sulfate
Gastrointestinal Effects	Lower incidence of constipation, nausea, and stomach cramps.	Higher incidence of gastrointestinal upset, including constipation and stomach pain.
Absorption Rate	Slower, more gradual absorption.	Rapid absorption, which can cause irritation.
Elemental Iron Content	Typically higher elemental iron content per dose.	Lower elemental iron content, often requiring multiple tablets or higher dosage.
Tolerance	Generally well-tolerated, suitable for sensitive individuals.	Can be poorly tolerated, leading some patients to discontinue treatment.

Potential Side Effects and Considerations

Although generally well-tolerated, polysaccharide iron tablets can still have side effects, usually mild and temporary.

Common side effects:
- Constipation or diarrhea
- Stomach pain or cramps
- Dark or black stools (normal and harmless)
- Mild nausea
Interactions: This iron supplement can interact with certain medications and foods. Avoid antacids for two hours before or four hours after taking the tablet. Dairy, eggs, and caffeine can also hinder absorption and should be avoided around the time of taking the supplement.
Overdose: Accidental overdose is serious, especially in children. Seek immediate medical help in case of overdose.

Conclusion

Polysaccharide tablets, containing polysaccharide iron complex, are crucial for preventing and treating iron deficiency and anemia. Their high bioavailability and better tolerability make them a preferred choice for those sensitive to other oral iron supplements. Whether for pregnancy, chronic blood loss, or general deficiency, these tablets offer an effective way to restore iron levels. Always follow a healthcare professional's guidance on dosage and treatment duration. For more detailed information, consult scientific literature on polysaccharide iron complex.

List of Uses

Treating and preventing iron deficiency anemia.
Providing iron supplementation during pregnancy.
Supporting individuals with chronic blood loss.
Meeting increased iron needs during periods of rapid growth.
Supplementing iron levels in patients with chronic kidney disease.
Aiding recovery following surgery.
Improving energy and reducing fatigue caused by anemia.

Note: Always consult a healthcare professional before starting any new iron supplement.

Frequently Asked Questions

Polysaccharide iron is generally better tolerated and causes fewer gastrointestinal side effects like constipation and stomach upset compared to ferrous sulfate. This is due to its slow-release, chelated structure.

Yes, polysaccharide iron complex is often used as an iron supplement during pregnancy to meet increased iron requirements and prevent anemia, but it should only be taken under medical supervision.

For best absorption, it is often recommended to take polysaccharide iron tablets on an empty stomach, about one hour before or two hours after a meal. If stomach upset occurs, taking it with a small amount of food is an option.

Dark or black-colored stools are a harmless and common side effect of taking any oral iron supplement, including polysaccharide tablets. This is simply a result of unabsorbed iron passing through the digestive system.

Polysaccharide iron complex is considered safe for children when administered under the supervision of a doctor. The proper dosage will be determined based on the child's age and weight.

Avoid taking polysaccharide iron tablets with calcium-rich foods (like dairy), tea, coffee, or eggs, as they can interfere with iron absorption. Take the supplement a few hours before or after these items.

Improvement in iron levels can be seen within a few weeks, but it may take several months of consistent use to fully replenish the body's iron stores and correct anemia. The exact duration depends on the severity of the deficiency.