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What are the benefits of kidney extract? Separating Fact from Fiction

4 min read

Over half of U.S. adults use dietary supplements, seeking everything from energy boosts to organ support. Among the more niche products are animal-derived glandulars, including supplements marketed with claims about what are the benefits of kidney extract. However, a closer look at the science and expert opinions reveals significant gaps between marketing promises and credible evidence.

Quick Summary

This article explores the alleged benefits of kidney extract, contrasting marketing claims with the lack of credible scientific evidence for its efficacy. It discusses the nutritional value of fresh organ meat versus processed extracts, potential risks, and highlights the importance of evidence-based nutrition for kidney health.

Key Points

  • No Scientific Proof: Credible human clinical research does not support claims that kidney extract improves kidney function, aids detoxification, or prevents disease.

  • Risks for Kidney Patients: Individuals with reduced kidney function face significant risks from unregulated supplements, particularly due to potentially uncontrolled levels of potassium and phosphorus.

  • Nutrient Misrepresentation: The high nutrient density of fresh kidney meat is often used in supplement marketing, but is misleading, as processed extracts contain minimal, and often unverified, nutrient levels.

  • Histamine Intolerance is Possible, but Unproven: The only potential, but weakly-evidenced, benefit relates to histamine intolerance due to the DAO enzyme content in animal kidneys.

  • Better Alternatives Exist: Safer and more effective approaches for supporting kidney health include a balanced diet, proper hydration, and clinically backed supplements like fish oil, vitamin D, zinc, and selenium under medical guidance.

  • Contaminant Risk: As a filtering organ, animal kidneys can accumulate heavy metals, and supplement safety is compromised without rigorous third-party testing for contaminants.

In This Article

What is Kidney Extract?

Kidney extract, or glandular, is a dietary supplement derived from freeze-dried animal kidneys, typically from cows (bovine) or pigs (porcine). The practice is rooted in the "like supports like" theory, a pre-modern medical belief that consuming an animal organ can strengthen the corresponding organ in humans.

Supplement companies often promote these products by highlighting their purported nutrient density, which is based on the contents of fresh kidney meat. However, there is a stark difference between the whole food and a processed, encapsulated extract.

The Lack of Scientific Evidence for Kidney Health

Despite aggressive marketing tactics that suggest kidney extract can detoxify the body or enhance organ function, credible human clinical research to support these claims is nonexistent.

  • The National Kidney Foundation states that healthy kidneys do not require "detox" supplements and that unproven remedies can sometimes cause harm.
  • Harvard Health Publishing has also confirmed that the organ-specific benefits derived from eating animal organs have no scientific basis in human research.
  • Research often cited by supplement brands to support these claims is either based on animal studies or involves isolated compounds, which do not translate directly to human results from consuming a dried, non-standardized extract.

Potential Benefits and Risks of Kidney Extract

While the general claims for kidney support lack evidence, some specific applications have been explored, along with serious potential risks.

A Note on Histamine Intolerance One area of potential, though weakly supported, benefit relates to histamine intolerance.

  • DAO Enzyme Source: Animal kidneys are a natural source of the enzyme diamine oxidase (DAO), which helps break down histamine in the body.
  • Mineral Cofactors: The kidneys contain minerals like copper and zinc, which are cofactors for DAO activation.
  • Limited Evidence: While some in vitro (test tube) studies using pig kidney extracts have shown promising results, robust human studies confirming effectiveness for histamine intolerance are lacking.

Serious Potential Risks For individuals with pre-existing kidney conditions, consuming unregulated glandular supplements can be dangerous.

  • Mineral Imbalance: Kidney extracts can contain uncontrolled and potentially harmful levels of minerals like potassium and phosphorus. For those with reduced kidney function, excess potassium can be life-threatening.
  • Heavy Metal Contaminants: As a filtering organ, animal kidneys can accumulate heavy metals, pesticides, and other environmental toxins from the source animal. Without rigorous third-party testing and standardization, these contaminants could end up in the supplement.
  • False Security: Relying on unproven supplements can cause individuals to delay seeking proper medical care for kidney-related symptoms, which can lead to worse health outcomes.

Fresh Kidney vs. Supplement: Nutritional Comparison

It's important to distinguish between the nutritional content of fresh, whole kidney meat and the often-minimal, unverified contents of dried capsules.

Nutrient Fresh Beef Kidney (per 100g) Standard Kidney Extract Capsule (per serving)
Protein ~27 g ~2-4 g (if included)
Vitamin B12 >1000% Daily Value Unverified (likely a fraction)
Selenium >300% Daily Value Unverified (likely a fraction)
Iron 58% Daily Value Unverified (likely a fraction)
Phosphorus ~304 mg Unverified (potential risk)
Potassium ~135 mg Unverified (potential risk)

This table illustrates the significant difference in nutrient density. The high processing and minimal serving sizes of supplements mean the nutrient levels are substantially lower and may not be consistently delivered.

Evidence-Based Alternatives for Kidney Health

For those interested in supporting kidney health, a sound nutritional diet and clinically proven supplements are far more effective than unverified extracts.

  • Balanced Diet: The foundation of kidney health is a balanced diet rich in fruits, vegetables, whole grains, and lean proteins, with limited salt, sugar, and saturated fats.
  • Adequate Hydration: Drinking plenty of fluids is essential for proper kidney function.
  • Omega-3 Fatty Acids: EPA and DHA, found in fish oil, may help reduce the risk of kidney stones.
  • Trace Element Supplementation: For individuals with Chronic Kidney Disease (CKD), trace elements like zinc and selenium can be beneficial, but only under a doctor's supervision.
  • Vitamin D: Healthy kidneys activate vitamin D, and supplementation may be needed for those with impaired function.
  • Antioxidant Support: Plant-based antioxidants, such as those found in cranberries, have been shown to provide benefits, including anti-inflammatory effects.

Conclusion

In conclusion, the idea that kidney extracts can significantly improve overall kidney health or provide detoxification benefits is not supported by credible scientific evidence. Marketing claims often rely on outdated theories and misleading comparisons to the nutrient density of fresh organ meat. Given the potential risks associated with unregulated supplement ingredients, especially for individuals with kidney issues, they are not a recommended or reliable solution. Instead, focusing on a balanced nutritional diet, adequate hydration, and consulting healthcare professionals for kidney health concerns is the safest and most effective approach. For those with specific conditions like histamine intolerance, any potential benefit is far from proven and should be discussed with a doctor. The best path to a healthier life involves proven, evidence-based practices, not unsubstantiated supplements.

Disclaimer

Consult a healthcare professional before taking any new supplement, especially if you have pre-existing health conditions or are on medication. This article is for informational purposes only and does not constitute medical advice.

Frequently Asked Questions

No, this is a misleading claim. Your healthy kidneys naturally filter waste and detoxify the body without needing supplements. The National Kidney Foundation warns against unproven detox remedies.

No, kidney extract supplements are not a reliable source of nutrients. While fresh kidney meat is nutrient-dense, the minimal serving sizes and processing of extracts mean the nutrient levels are often low and unverified.

You should avoid taking kidney extract if you have any kidney condition. The unregulated levels of minerals like potassium and phosphorus can be dangerous, and the supplements may contain harmful contaminants.

No, the "like supports like" theory is an outdated belief with no credible scientific basis in modern medicine. There is no evidence that consuming an animal organ strengthens your own corresponding organ.

Evidence for using kidney extract for histamine intolerance is weak and based mainly on in vitro (test tube) studies. Animal kidneys contain the DAO enzyme, but more research is needed to prove efficacy in humans.

Proven alternatives include maintaining a balanced diet with plenty of fruits and vegetables, staying hydrated, and consulting a doctor about specific, evidence-backed supplements like Vitamin D or fish oil, if needed.

It is critical to consult a healthcare provider because they can assess your specific health needs and risks. Unproven supplements can interfere with medications, cause harm due to inconsistent ingredients, and potentially delay proper diagnosis and treatment.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.