Digestive Issues and Gastrointestinal Discomfort
One of the most common complaints associated with consuming garlic, particularly raw or in large quantities, is gastrointestinal distress. The primary culprits are fructans, a type of fermentable carbohydrate found in high concentrations in garlic and other allium vegetables like onions and leeks. For people with irritable bowel syndrome (IBS) or sensitivity to FODMAPs (fermentable oligo-, di-, mono-saccharides and polyols), the fermentation of fructans in the gut can lead to uncomfortable symptoms.
Common digestive symptoms include:
- Bloating and excessive gas
 - Stomach pain and cramping
 - Diarrhea or constipation
 - Nausea and vomiting
 
Garlic can also contribute to acid reflux and heartburn, especially in individuals with gastroesophageal reflux disease (GERD). This occurs because garlic may decrease the tone of the lower esophageal sphincter (LES), the muscle that prevents stomach acid from flowing back into the esophagus. Raw garlic, due to its potency, is more likely to trigger these symptoms than cooked garlic.
Increased Risk of Bleeding
Garlic possesses antithrombotic properties, meaning it can inhibit platelet aggregation and slow blood clotting. This is a potential health risk for certain groups, particularly those taking blood-thinning medications or preparing for surgery.
- Interactions with medication: High doses of garlic or garlic supplements can increase the risk of bleeding when taken with anticoagulants like warfarin or antiplatelet drugs like aspirin. Combining these substances can increase the likelihood of bruising, nosebleeds, and excessive bleeding from cuts.
 - Surgical procedures: Medical professionals advise stopping garlic supplements and large quantities of fresh garlic at least two weeks before a scheduled surgery to minimize the risk of prolonged bleeding.
 
Allergic Reactions and Dermatitis
While relatively rare, some individuals have a genuine allergy to garlic, which can range from mild to severe. Symptoms can manifest from consuming garlic or even from direct skin contact or inhaling garlic dust.
- Symptoms of a garlic allergy: A true allergic reaction can cause hives, itching, skin redness, swelling of the mouth, tongue, or throat, wheezing, and in severe cases, anaphylaxis.
 - Contact dermatitis: The topical application of raw garlic is considered unsafe and can cause severe skin irritation, blistering, and chemical burns. This occurs due to the allicin and other sulfur compounds in fresh garlic.
 - Cross-reactivity: Since garlic belongs to the allium family, those allergic to garlic may also experience cross-reactivity with other related vegetables, such as onions, leeks, and chives.
 
Unpleasant Breath and Body Odor
Garlic's distinctive, pungent odor is a well-known side effect, but the smell is not limited to bad breath. The odor is caused by volatile sulfur compounds, such as allyl methyl sulfide (AMS).
- How the odor is released: After consuming garlic, the body metabolizes these sulfur compounds, which are then absorbed into the bloodstream. The compounds are released through the lungs, causing persistent breath odor, and expelled through skin pores, resulting in a pervasive body odor.
 - Ineffective remedies: Standard oral hygiene practices like brushing and using mouthwash are often ineffective at eliminating garlic odor because much of the smell originates from the lungs and skin, not just the mouth.
 
Comparison of Raw vs. Cooked Garlic
| Characteristic | Raw Garlic | Cooked Garlic | 
|---|---|---|
| Digestive Issues | Higher likelihood and intensity of symptoms due to higher fructan and allicin content. | Lower likelihood and intensity of digestive discomfort, as cooking can reduce the potency of certain compounds. | 
| Bad Breath/Body Odor | Stronger and more persistent odor due to higher concentrations of sulfur compounds released. | Odor is typically less pronounced because the cooking process can degrade some of the volatile sulfur compounds. | 
| Bleeding Risk | Potent antithrombotic effects, requiring caution, especially with supplements. | Milder antithrombotic effect; regular food amounts generally safe for most individuals. | 
| Allergy & Skin Irritation | Potential for more severe allergic reactions and is unsafe for topical application due to risk of chemical burns. | Cooking can reduce the allergenic potential for some, making it less likely to trigger a reaction. | 
| Drug Interactions | Significant potential for interaction with various medications, particularly blood thinners. | Interactions less significant in culinary amounts but still a concern with large, consistent consumption. | 
Other Health Considerations
In addition to the primary side effects, there are specific situations and health conditions where caution with garlic is necessary.
- Drug interactions beyond anticoagulants: Garlic has been shown to interact with several other medications, including certain drugs for HIV/AIDS (protease inhibitors), blood pressure medications, and immunosuppressants like tacrolimus. Patients on these drugs should consult a healthcare provider before taking garlic supplements.
 - Low blood pressure: For individuals with naturally low blood pressure, excessive garlic consumption might cause blood pressure to drop further, leading to dizziness.
 - Pregnancy and breastfeeding: While culinary amounts are generally safe, medicinal quantities of garlic are considered possibly unsafe during pregnancy and breastfeeding due to a lack of sufficient research.
 
Conclusion
While garlic is a potent ingredient with various potential health benefits, it is not without its downsides. For some, the negative effects of garlic, such as digestive problems, strong body odor, and potential bleeding risks, can outweigh the benefits. Understanding your personal tolerance, being mindful of excessive intake, and considering raw versus cooked forms can help mitigate some of these issues. Individuals with pre-existing conditions or those on specific medications should consult a healthcare professional before significantly increasing their garlic intake or beginning supplementation. Moderation and awareness are key to enjoying garlic safely and comfortably. For more information on food sensitivities, you can consult reputable health resources like the National Center for Complementary and Integrative Health (NCCIH).