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What Are the Only Two Essential Fatty Acids?

3 min read

According to the National Institutes of Health, the human body cannot produce linoleic acid and alpha-linolenic acid, making them the only two essential fatty acids. These two fundamental fats, one from the omega-6 family and the other from the omega-3 family, are the building blocks for more complex fats the body uses for energy, cell structure, and regulating inflammation.

Quick Summary

The two essential fatty acids are linoleic acid (omega-6) and alpha-linolenic acid (omega-3). Both are polyunsaturated fats vital for health and must be consumed through diet.

Key Points

  • Essential Fatty Acids: The two you must get from your diet are linoleic acid (LA) and alpha-linolenic acid (ALA).

  • Linoleic Acid (LA): This is an omega-6 fatty acid found in many vegetable oils, nuts, and seeds; it serves as a precursor for other omega-6s.

  • Alpha-Linolenic Acid (ALA): This is an omega-3 fatty acid found in plant sources like flaxseed, walnuts, and chia seeds; it is a precursor to EPA and DHA.

  • Inflammation and Balance: Omega-6s are generally more pro-inflammatory, while omega-3s are anti-inflammatory. A balanced ratio is crucial for health.

  • Modern Dietary Imbalance: Western diets often contain excessive omega-6 and insufficient omega-3, which can contribute to chronic inflammation.

  • Critical Functions: Both LA and ALA are vital for building cell membranes, providing energy, and producing important signaling molecules.

In This Article

The Two Essential Fatty Acids Explained

There are only two fatty acids that the human body cannot produce on its own: linoleic acid (LA) and alpha-linolenic acid (ALA). Both are polyunsaturated fatty acids (PUFAs) with 18 carbon atoms and play unique, critical roles in maintaining health. While they share the classification of being "essential," they come from different families—LA is an omega-6 fatty acid and ALA is an omega-3 fatty acid.

Linoleic Acid (LA): The Omega-6 Essential Fatty Acid

Linoleic acid serves as the parent fatty acid for the entire omega-6 family. Our bodies use LA to synthesize longer-chain omega-6 fats, such as arachidonic acid (AA), which is a component of cell membranes and a precursor to signaling molecules called eicosanoids.

Sources of Linoleic Acid Most Western diets are rich in sources of LA. Common dietary sources include vegetable oils (like safflower, corn, and soybean oil), nuts and seeds, and poultry and eggs.

Alpha-Linolenic Acid (ALA): The Omega-3 Essential Fatty Acid

Alpha-linolenic acid is the parent fatty acid for the omega-3 family. It is a plant-based omega-3 that the body can use to produce longer-chain omega-3s, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). However, this conversion process is notoriously inefficient in humans, making dietary intake of EPA and DHA (found in fish oil) important for optimal health.

Sources of Alpha-Linolenic Acid Unlike LA, ALA can be less prevalent in modern diets. Key sources include flaxseed and flaxseed oil, chia seeds, walnuts, canola oil, and soybean oil.

Their Critical Role in the Body

Both essential fatty acids are vital for numerous physiological processes. Their primary functions include maintaining cellular membrane structure, providing energy for growth and development, and serving as precursors to signaling molecules that regulate inflammation. Omega-3 derived eicosanoids are generally anti-inflammatory, while omega-6 derived eicosanoids are pro-inflammatory. DHA, derived from ALA, is also important for brain and nervous system function.

The Importance of Balancing Omega-6 and Omega-3 Intake

While both LA and ALA are essential, the ratio of their intake significantly impacts health. The Western diet typically has a much higher ratio of omega-6 to omega-3 (10:1 to 20:1) than is considered healthy. This imbalance can contribute to chronic inflammation. To restore balance, it is recommended to increase omega-3 intake through sources like fatty fish, flaxseeds, and walnuts.

Comparison of Essential Fatty Acids

Feature Linoleic Acid (LA) Alpha-Linolenic Acid (ALA)
Family Omega-6 Omega-3
Classification Polyunsaturated Fatty Acid (PUFA) Polyunsaturated Fatty Acid (PUFA)
Primary Sources Safflower oil, corn oil, sunflower seeds, nuts, poultry Flaxseed, walnuts, chia seeds, canola oil, soybeans
Metabolites Arachidonic Acid (AA) Eicosapentaenoic Acid (EPA) & Docosahexaenoic Acid (DHA)
Typical Eicosanoids Pro-inflammatory Anti-inflammatory
Typical Western Diet Often over-consumed relative to ALA Often under-consumed relative to LA
Key Benefit Cell membrane health, normal growth Supports heart, brain, and vision health

Signs of Essential Fatty Acid Deficiency

Severe EFA deficiency is uncommon in healthy individuals with a balanced diet but can occur with long-term intravenous feeding lacking PUFAs. Symptoms may include dry, scaly skin, growth issues in infants, poor wound healing, increased infections, and neurological/visual problems.

Conclusion: Fueling Your Body with Essential Fats

Understanding that linoleic acid (omega-6) and alpha-linolenic acid (omega-3) are the only two essential fatty acids is key to a healthy diet. While both are necessary, the typical Western diet often has too much omega-6 and not enough omega-3. Increasing ALA-rich foods like flaxseeds and walnuts, along with EPA and DHA from fatty fish, can improve this balance and offer significant health benefits, particularly in managing inflammation and supporting cardiovascular and neurological health.

Visit the Linus Pauling Institute for more in-depth information on essential fatty acids and their roles in health

Frequently Asked Questions

Linoleic acid is an essential omega-6 fatty acid that serves as a precursor to other omega-6 fats, such as arachidonic acid. It is crucial for cell membrane structure, providing energy, and maintaining healthy skin.

Humans lack the necessary enzymes (specifically, delta-12 and delta-15 desaturases) to insert double bonds at the omega-6 and omega-3 positions of the fatty acid chain, meaning they must be consumed through the diet.

Both omega-3 and omega-6 fatty acids are essential and important. The key is maintaining a healthy balance between the two, as modern diets often contain an excess of omega-6s compared to omega-3s.

Severe deficiency is rare but can lead to symptoms such as dry, scaly skin, dermatitis, stunted growth in infants, poor wound healing, and neurological problems.

Yes, the body can convert ALA into EPA and DHA, but this process is very inefficient. Therefore, it is recommended to get EPA and DHA directly from dietary sources like fatty fish to ensure adequate levels.

No, EPA and DHA are not considered essential fatty acids because the body can technically produce them from ALA. However, due to the low conversion rate, they are often referred to as 'conditionally essential' because direct intake is more effective for optimal health.

Flaxseed and flaxseed oil are excellent plant-based sources of alpha-linolenic acid (ALA). Other good sources include walnuts, chia seeds, and canola oil.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.